Clomid sometimes referred to as “Clomifert” belongs to a class of drugs that acts upon the estrogen receptors in somewhat of a selective manner. A common mistake many make when talking about Clomid is placing it in the same category as aromatase inhibitors such as Femara (Letrozole) and Anastrozole (Arimidex) when in-fact both of the later, although carrying some similar traits are actually very different. For example, for those who use the drugs for performance enhancing purposes, Clomid has the ability to block estrogen, while the aromatase inhibitors actually have the ability to not only block but reduce.

Clomid was not designed for performance enhancing purposes, although that use has become very common in recent years. Clomid was originally designed for the purpose of ovarian stimulation in women who have trouble becoming pregnant. In some cases a woman will suffer from what is known as Chronic Anovulation, which in short is a form of menstrual cycle in-which ovulation does not occur. The failure of this ovulation results in an absence of oocyte, a germ cell necessary for reproduction. Clomid can be successfully used to treat and remedy this problem.

However, in recent years, Clomid has become popular in many performance enhancing circles as both an on cycle drug to combat issues of estrogen buildup that can lead to side-effects such as Gynecomastia, as well as part of a post cycle therapy plan to increase and stimulate natural testosterone production after a course of anabolics is complete. Many credit the late Dan Duchaine as the individual who first made Clomid popular among Anabolic steroid users and since Duchaine it has remained a staple for many. 

Clomid although useful for combating symptoms such as Gynecomastia is far more suited for post cycle therapy needs. Although Clomid may indeed get the job done during an Anabolic steroid cycle, drugs such as Femara (Letrozole) and Anastrozole (Arimidex)are for more beneficial to serve this purpose; especially in those who are predisposed to the problem. 

Although Clomid is still used by many during their post cycle treatment the drug Tamoxifen (Nolvadex or Nolva) has largely become more popular. Milligram for milligram Tamoxifen is stronger than Clomid and does not carry the blurred vision side-effect common among some Clomid users. Although blurred vision is not a side-effect shared by the majority of Clomid users it has been reported by some; although mild and discontinues when therapy is stopped. Some users further report abdominal discomfort from use; however this is again very rare. 

Although Clomidremains popular in many circles, it is slowly but surely losing some of its appeal due to a higher concentrated use of Tamoxifen, Femara and Anastrozole. Some Anabolic steroid users, especially in bodybuilding circles where doses are often higher and run for longer periods of time have begun using Clomid in conjunction with Tamoxifen for their post cycle therapy; it is safe but many argue unnecessary. In general, one or the other will get the job done, especially if hCG is used as part of the post cycle therapy plan.

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